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PathWays Case Study: October 20



A 57-year-old woman with a history of acute myeloid leukemia presented with lower extremity edema and weight gain one year following hematopoietic stem cell transplantation (HCT). Her laboratory findings indicate normal renal function, hypoalbuminemia, and a 24-hour urine protein of 1271 mg (normal limits = <167 mg/ 24 hour). Serological studies for complements, antineutrophil antibody (ANA), and antineutrophil cytoplasmic antibody (ANCA) were unremarkable. The serum protein electropheresis (SPEP) and urine protein electropheresis (UPEP) are negative for para-proteins.

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Osamah (Sam) AL Badrim M.B., Ch.B.

Osamah (Sam) AL-Badri, M.B., Ch.B.
Resident, Anatomic Pathology
Mayo Clinic




Mariam (Priya) Alexander, M.D.

Mariam (Priya) Alexander, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine



April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.