PathWays Case Study: December 1

A 24-year-old female college student presents to the ER with anxiety, confusion, psychomotor agitation, acute suicidal ideation, and reported seizure. There is prior history of bipolar mood disorder. Head CT scan and MRI are normal. EEG shows nearly continuous right posterior focal seizures with some generalization to the left hemisphere. Antibody work up for autoimmune encephalitis revealed anti-N-methyl-D-aspartate receptor antibodies (NMDAR antibodies). Therapy with intravenous corticosteroids, IVIG, and plasma exchange is begun with improvement in seizure activity, neurology symptoms, and psychiatric symptoms.

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Karamzadeh Dashti_Nooshin_13JU

Nooshin Karamzadeh Dashti, M.D.
Resident, Anatomic/Clinical Pathology
Mayo Clinic

 

 

 

Jeffrey Winters, M.D.

Jeffrey Winters, M.D.
Consultant, Division of Transfusion Medicine
Mayo Clinic
Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine

apriljosselyn

apriljosselyn

April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.