Mayo Clinic Laboratory and Pathology Research Roundup: April 18
The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including a featured article of the week, abstracts, and complete list of published studies and reviews.
Featured Study of the Week
Assessing the Value of LMO2 as a Biomarker for T-Lymphoblastic Leukemia/Lymphoma
T-lymphoblastic leukemia/lymphoma (also known as T-cell acute lymphoblastic leukemia or “T‑ALL”) is an aggressive cancer caused by an overproduction of immature T cells. Recent research suggests that the protein LMO2 appears to be a biomarker of transformed T‑precursor cells. In a recent study published in the American Journal of Clinical Pathology, Mayo Clinic researchers tested the specificity of LMO2 for distinction between neoplastic and non-neoplastic T-precursor cells in the thymus and bone marrow.
Published to PubMed This Week
- Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer
Cell Reports - Clinical and Immunologic Investigations in Patients With Stiff-Person Spectrum Disorder
JAMA Neurology - Pancreatic Cyst Epithelial Denudation: a Natural Phenomenon in the Absence of Treatment
Gastrointestinal Endoscopy - Morphologic Features of ALK-negative Anaplastic Large Cell Lymphomas With DUSP22 Rearrangements
American Journal of Surgical Pathology - Cefepime Susceptible-Dose-Dependent MIC for Enterobacteriaceae: Impact on Reporting and Prescribing
Antimicrobial Agents and Chemotherapy - Molecular Correlates of Anemia in Primary Myelofibrosis: A Significant and Independent Association With U2AF1 Mutations
Blood Cancer Journal - Survival Trends in Primary Myelodysplastic Syndromes: A Comparative Analysis of 1000 Patients By Year of Diagnosis and Treatment
Blood Cancer Journal - Direct Electrical Current Reduces Bacterial and Yeast Biofilm Formation
International Journal of Bacteriology - Adenocarcinoma in Situ, Minimally Invasive Adenocarcinoma, and Invasive Pulmonary Adenocarcinoma-Analysis of Interobserver Agreement, Survival, Radiographic Characteristics, and Gross Pathology in 296 Nodules
Human Pathology