PathWays Case Study for April 26



A 90-year-old man with symptomatic severe aortic stenosis underwent elective percutaneous (transcatheter) native aortic valve replacement with a bovine bioprosthetic valve. Immediately following the procedure, the patient became hemodynamically unstable, developed a large femoral hematoma at the site of catheterization, and a large prosthetic valve mass was noted on echocardiogram. Despite supportive measures, the patient continued to deteriorate and expired approximately 12 hours following the procedure. An autopsy was performed.

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Charles Leduc, M.D., C.M.
Resident, Cardiovascular Pathology
Mayo Clinic





Dr. Joseph Maleszewski

Joseph Maleszewski, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology and Associate Professor of Medicine,
Mayo Clinic College of Medicine
Follow him on Twitter: @joemaleszewski



April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.