A 27-year-old woman complains of mild back and shoulder pain for several months. In the past few weeks, she has developed dyspnea, cough, fatigue, weight loss, and decreased appetite. Chest X-ray showed opacification of the right hemithorax, and follow-up CT showed a 20 cm pleural-based lung mass involving the right chest. Large areas of cystic change or necrosis are noted on imaging. Core biopsy of the mass was performed (see photomicrographs).
Jennifer Boland Froemming, M.D.
Consultant, Division of Anatomic Pathology
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine