PathWays Case Study for May 24

A 77-year-old man had progressive dyspnea with exertion and slight left anterior chest wall pain. He was later diagnosed with sarcomatoid carcinoma of the mandible and maxilla and treated with resection and adjuvant radiation therapy. Postoperatively, he developed worsening dyspnea and pericardial effusion with evidence of tamponade and died two months later. A pleural lesion was identified at autopsy (figures).


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Xuemei Wu, B.Med., Ph.D.
Resident, Anatomic Pathology Residency
Mayo Clinic






Anja Roden, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine



April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.