Mayo Clinic Laboratory and Pathology Research Roundup: June 27

By brentwestra • June 27, 2016

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including a featured article of the week, abstracts, and complete list of published studies and reviews.

Featured Study of the Week

Prognostic Value of Circulating Tumor Cell Enumeration in Patients with Cholangiocarcinoma

Cholangiocarcinoma (CCA) is the second most common cause of primary liver cancer. Currently, useful prognostic and predictive biomarkers for CCA do not exist, resulting in diagnosis at an advanced stage with no effective treatment options. Circulating tumor cells (CTCs) in the peripheral blood are associated with various types of cancer. Mayo Clinic researchers hypothesized that CTCs are also associated with poor survival of patients with CCA. The study was published in the Hepatology journal.

Published to PubMed This Week

• C4d as a Marker for Masked Immune Deposits
  Kidney International
• Silent Diabetic Nephropathy
  Kidney International
• Necrotizing Subconjunctival Granulomata and Intraoperative Use of Topical GenTeal Gel
  Ophthalmology
• Recurrent Light Chain Proximal Tubulopathy in a Kidney Allograft
  American Journal of Kidney Diseases
  
• Human Gut-Derived Prevotella histicola Suppresses Inflammatory Arthritis in Humanized Mice
  Arthritis & Rheumatology
• Pregnancy Outcomes Related to Mycophenolate Exposure in Female Kidney Transplant Recipients
  American Journal of Transplantation
• Multiple-Level Validation Identifies PARK2 in the Development of Lung Cancer and Chronic Obstructive Pulmonary Disease
  Oncotarget
• Improving Survival From Cardiac Arrest: A Review of Contemporary Practice and Challenges
  Annals of Emergency Medicine
• Effect of Chair Types on Work-Related Musculoskeletal Discomfort During Vaginal Surgery
  American Journal of Obstetrics & Gynecology
• A Novel Treatment Schedule for Rapid Completion of Surgery and Radiation in Early-Stage Breast Cancer
  Annals of Surgical Oncology
• Hypoxia-Related microRNA-210 is a Diagnostic Marker for discriminating Osteoblastoma and Osteosarcoma
  Journal of Orthopaedic Research
• Glioblastoma Arising Within a Mediastinal Mature Teratoma
  Human Pathology
• Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies
  Genetic Epidemiology
• Thyroid Hormone Testing in the 21st Century
  Clinical Biochemistry
• Lymphoplasmacytic Lymphoma With a Non-IgM Paraprotein Shows Clinical and Pathologic Heterogeneity and May Harbor MYD88 L265P Mutations
  American Journal of Clinical Pathology
• Myxoid Hepatocellular Neoplasms: Imaging Appearance of a Unique Mucinous Tumor Variant
  Abdominal Radiology

brentwestra

Brent Westra is a Marketing Segment Manager at Mayo Clinic Laboratories. He leads marketing strategies for product management and specialty testing along with new media innovations. Brent has worked at Mayo Clinic since 2011.