Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 29

By brentwestra • August 29, 2016

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Individualized Approaches are Needed for Optimized Blood Cultures

Many strategies and technologies are available that strive to improve blood culture (BC)-based diagnostics. The ideal approach to BCs varies between health care institutions. Institutions need to examine clinical needs and practices in order to optimize BC-based diagnostics for their site. Before laboratories consider offering rapid MALDI-ToF MS or expensive rapid panel-based molecular BC diagnostics, they should optimize pre-analytical, analytical and post-analytical processes and procedures surrounding BC systems. Several factors need to be considered, including local resistance rates, antibiotic prescribing patterns, patient- and provider-types, laboratory staffing, and personnel available to liaise with clinicians to optimize antibiotic use. While there is much excitement surrounding new high-technology diagnostics, cost-neutral benefits can be realized by optimizing existing strategies and using available tools in creative ways. Implementation of rapid BC diagnostics should be done in a manner that optimizes impact. Strategies to optimize these BC diagnostics in individual laboratories are presented. The statement was published in Clinical Infectious Diseases.

Published to PubMed This Week

• Comprehensive Assessment of M-Proteins Using Nanobody Enrichment Coupled to MALDI-TOF Mass Spectrometry
  Clinical Chemistry
• Individualizing Immunosuppressive Therapy for Transplant Patients
  Clinical Chemistry
• New Developments in Clinical Bacteriology Laboratories
  Mayo Clinic Proceedings
• Activity of Tedizolid in Methicillin-Resistant Staphylococcus aureus Experimental Foreign Body-Associated Osteomyelitis
  Antimicrobial Agents and Chemotherapy
  
• Medical Malpractice in the Management of Small Bowel Obstruction: A 33-Year Review of Case Law
  Surgery
• Primary Angiomatoid Fibrous Histiocytoma of the Lung with Mediastinal Lymph Node Metastasis
  Human Pathology
• Adenocarcinoma in Situ, Minimally Invasive Adenocarcinoma, and Invasive Pulmonary Adenocarcinoma--Analysis of Interobserver Agreement, Survival, Radiographic Characteristics, and Gross Pathology in 296 Nodules
  Human Pathology
• Complications and Outcomes Associated with Surgical Management of Renal Cell Carcinoma Involving the Liver: a Matched Cohort Study
  Urology
• Imaging Characteristics of Intravascular Papillary Endothelial Hyperplasia
  Skeletal Radiology
  
• Khat Chewing and Cirrhosis in Somaliland: Case Series
  African Journal of Primary Health Care & Family Medicine

brentwestra

Brent Westra is a Marketing Segment Manager at Mayo Clinic Laboratories. He leads marketing strategies for product management and specialty testing along with new media innovations. Brent has worked at Mayo Clinic since 2011.