Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 10

By brentwestra • October 10, 2016

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Noninvasive Assessment of Renal Fibrosis with Magnetization Transfer MR Imaging: Validation and Evaluation in Murine Renal Artery Stenosis

Mayo Clinic researchers conducted a study to test the utility of magnetization transfer imaging in detecting and monitoring the progression of renal fibrosis in mice with unilateral renal artery stenosis. In the stenotic kidney, the median magnetization transfer ratio showed progressive increases from baseline to six weeks after surgery, which were accompanied by a progressive loss in renal volume, perfusion, blood flow, and oxygenation. Based on the results, magnetization transfer imaging was used successfully to measure and longitudinally monitor the progression of renal fibrosis in mice with unilateral renal artery stenosis. The study was published in Radiology. 

Published to PubMed This Week

• Does Sudden Unexplained Nocturnal Death Syndrome Remain the Autopsy-Negative Disorder: A Gross, Microscopic, and Molecular Autopsy Investigation in Southern China
  Mayo Clinic Proceedings
• Urinary Collecting System Invasion is Associated With Poor Survival in Clear Cell Renal Cell Carcinoma Patients
  BJU International
• Evaluation of Beta-Blockers and Survival Among Hypertensive Patients with Renal Cell Carcinoma
  Urologic Oncology
• Spindle Cell Lipomas Arising at Atypical Locations
  American Journal of Clinical Pathology
• High-Throughput Quantitation of Busulfan in Plasma Using Ultrafast Solid-Phase Extraction Tandem Mass Spectrometry (SPE-MS/MS)
  Methods in Molecular Biology

brentwestra

Brent Westra is a Marketing Segment Manager at Mayo Clinic Laboratories. He leads marketing strategies for product management and specialty testing along with new media innovations. Brent has worked at Mayo Clinic since 2011.