A nasopharyngeal (NP) swab collected from a 75-year-old female with fever, cough, sore throat, and body aches was submitted for a routine viral cell culture. After four days of incubation at 37°C, the following cytopathic effect (CPE) was observed in the primary rhesus monkey kidney cell line:
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Emily Fernholz, MLS(ASCP)
Education Specialist, Clinical Microbiology
Mayo Clinic
Instructor in Laboratory Medicine and Pathology
Mayo Clinic College of Medicine
Matthew Binnicker, Ph.D.
Consultant, Division of Clinical Microbiology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine
Viral culture, particularly centrifugation enhanced cultures, may be useful for less common specimen types not approved for PCR assays e.g. lung tissue,etc.