Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 14

By Kelley Luedke • November 14, 2016

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Hepatosplenic T-Cell Lymphoma with Blastoid Morphology in a Patient with Crohn Disease

A 33-year-old man with Crohn disease had been treated with azathioprine for 10 years and azathioprine/adalimumab for 9 months when he began experiencing fevers, fatigue, splenomegaly, and weight loss (20 lb in 6 months). Besides anemia and thrombocytopenia, his peripheral blood and bone marrow aspirate smears showed blastoid cells that were intermediate to large in size and had fine chromatin, prominent nucleoli, and irregular nuclear contours. View the case. The case was published in Blood.

Published to PubMed This Week

• Parkinson Disease
  Mayo Clinic Proceedings
• Biomarker-Based Risk Prediction in the Community
  European Journal of Heart Failure
• Atypical Notochordal Cell Tumors: A Series of Notochordal-derived Tumors That Defy Current Classification Schemes
  American Journal of Surgical Pathology
• Activity of Electrical Current in Experimental Propionibacterium acnes Foreign Body Osteomyelitis
  Antimicrobial Agents and Chemotherapy
• Precise Stimulation Location Optimizes Speech Outcomes in Essential Tremor
  Parkinsonism Related Disorders
• Optimal Periprosthetic Tissue Specimen Number for Diagnosis of Prosthetic Joint Infection
  Journal of Clinical Microbiology
• How Can Mate-Pair Sequencing Be Utilized for Cancer Patients?
  Expert Review of Molecular Diagnostics
• Clinical and Laboratory Characteristics in Congenital ANKRD26 Mutation-Associated Trombocytopenia: A Detailed Phenotypic Study of a Family
  Platelets
• Cardiac Angiosarcoma: Histopathologic, Immunohistochemical, and Cytogenetic Analysis of 10 Cases
  Human Pathology
• Diagnosis of Acute Cellular Rejection and Antibody-Mediated Rejection on Lung Transplant Biopsies: A Perspective From Members of the Pulmonary Pathology Society
  Archives of Pathology & Laboratory Medicine Online
• Detection of High-Risk Human Papillomavirus Infection in Tonsillar Specimens Using 2 Commercially Available Assays
  Diagnostic Microbiology and Infectious Disease
• The Modulating Effects of Cardiac Resynchronization Therapy on Myocardial Metabolism in Heart Failure
  Pacing and Clinical Electrophysiology
• Voluntary Second Opinions in Pediatric Bone and Soft Tissue Pathology: A Retrospective Review of 1601 Cases From a Single Mesenchymal Tumor Consultation Service
  International Journal of Surgical Pathology
• Biliary Tract Cancers: Epidemiology, Molecular Pathogenesis and Genetic Risk Associations
  Chinese Clinical Oncology
• Circulating Galectin-3 Levels Are Persistently Elevated After Heart Transplantation and Are Associated With Renal Dysfunction
  JACC: Heart Failure

Kelley Luedke

Kelley Luedke is a Marketing Channel Manager at Mayo Clinic Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her kitty, and exploring new foods.