A 51-year-old woman presented with two rounded right upper-lobe lung nodules, measuring 3.0 cm and 0.2 cm in greatest dimension. She underwent wedge resection of the masses. Histologic sections revealed the tumor was composed of two cell populations. All neoplastic cells stained positively with TTF-1 and epithelial membrane antigen (EMA) immunohistochemistry, while the lining cells also stained positively with pan-cytokeratin.
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Melanie Bois, M.D.
Fellow, Cardiovascular Pathology
Mayo Clinic
Follow her on Twitter: @MelanieBoisMD
Marie Christine Aubry, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine
Please send me such interesting cases in future.