PathWays Case Study: Dec. 20

A 25-year-old presented with a lesion on the left elbow, which was thought to a be a subcutaneous cyst. The lesion had been present for at least one year prior to excision. Grossly, it appeared to be cystic with mixed areas of hemorrhage. Immunohistochemically, the tumor cells are positive for desmin and negative for CD34, CD31, AE1/AE3, S-100, SOX-10, and Alk. Also, FISH showed findings consistent with an EWSR1 gene rearrangement.








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Kyle Perry

Kyle Perry, M.D.
Fellow, Bone and Soft Tissue Pathology
Mayo Clinic




folpe_andrew_l_16apAndrew Folpe, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine





Rene Revier

Rene Revier

Rene Revier is an Editorial Assistant at Mayo Medical Laboratories. She supports Mayo Clinic PathWays and other corporate communications activities.