PathWays Case Study: April 11

A renal biopsy was performed on a 75-year-old man from Mexico. His medical history was significant for diabetes and gout. He presented with proteinuria and renal failure. Serum creatinine was 3.5 mg/dL, and 24-hour urine protein was 628 mg. Light microscopy, immunoflourescent microscopy studies (IF), and electron microscopy were performed. IF was negative. H&E, Jones silver methenamine, and Congo red stains were performed and images are shown below:




Jones Sliver Methenamine


Congo Red

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Thomas (Tom) Czeczok, M.D.
Resident, Division of Anatomic and Clinical Pathology
Mayo Clinic



Mariam (Priya) Alexander, M.D.

Mariam (Priya) Alexander, M.D.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology,
Mayo Clinic College of Medicine and Science


Rene Revier (@renecre)

Rene Revier

Rene Revier is an Editorial Assistant at Mayo Medical Laboratories. She supports Mayo Clinic PathWays and other corporate communications activities.