PathWays Case Study: May 2

​A 46-year-old Caucasian male with a history of multiple blood transfusions underwent a blood type and antibody screen (T&S) upon admission to the hospital. The patient's blood type was determined to be O-negative, and the antibody screen was positive. Results of the subsequent antibody identification panel are provided below.

Additional communication with the patient's hematologist/oncologist revealed that the patient had a history of refractory multiple myeloma and had been receiving treatment with daratumumab for the past month. Given this new information, an additional antibody identification panel was performed using dithiothreitol (DTT) treated reagent red blood cells. Results of this DTT treated antibody identification panel are provided below:

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Brendan Graham, M.D.
Resident, Transfusion Medicine
Mayo Clinic

 

 

Jeffrey Winters, M.D.
Consultant, Division of Transfusion Medicine
Mayo Clinic
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Sciences

 

 

Eapen Jacob, M.D.
Consultant, Division of Transfusion Medicine
Mayo Clinic
Assistant Professor of Medicine and Pathology
Mayo Clinic College of Medicine and Sciences

apriljosselyn

apriljosselyn

April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.