PathWays Case Study: November 14

The patient is a 59-year-old man with a history of hyperthyroidism, gout, and hypertension. He presented to the emergency room with severe dehydration, electrolyte abnormalities, and a 50-pound weight loss due to severe chronic unexplained diarrhea. He described his stools as frequent (up to 30 per day), voluminous, and oily. Infectious panel including C. diff., HIV, hepatitis B, P-ANCA, and antiendomysial antibody was negative. Fasting serum gastrin was within normal limits.

The patient was hospitalized, and an endoscopy with biopsies was performed.

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Natalya Shlyakhova, M.D.
Fellow, Surgical Pathology
Mayo Clinic



Vishal Chandan, M.B.B.S.
Consultant, Division of Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine



April Josselyn (@apriljosselyn)

April Josselyn

April Josselyn is a Marketing Channel Manager at Mayo Clinic Laboratories. She has worked at Mayo Clinic since 2012. Outside of work, April enjoys the outdoors and being "hockey mom" for her two sports-crazed boys.