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January 2018 — Hematopathology 1

A 70-year-old female presented with peripheral blood lymphocytosis and hepatosplenomegaly. Below are the peripheral blood and bone marrow aspirate findings:

Karyotype cytogenetics revealed inv(14)(q11q32), with the rearrangement involving the TCL1 oncogene (confirmed by FISH).

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  Basma Basha, M.D.
Fellow, Hematopathology
Mayo Clinic
  Rebecca L. King, M.D.
Consultant, Division of Hematopathology
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine
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