Comments on: Frozen and on Time: Rapid Margin Assessment Helps Prevent Repeat Surgeries https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/ Get the latest news and education from Mayo Clinic Laboratories Fri, 18 Mar 2022 14:43:57 +0000 hourly 1 https://wordpress.org/?v=6.7.2 By: Kelley Schreiber https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28833 Wed, 04 Apr 2018 19:09:52 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28833 In reply to Richard Geller M.D..

Thank you for your comment, Dr. Geller. Please reach out to Dr. Keeney, interviewed in this article, directly with your questions at Keeney.Gary@mayo.edu.

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By: Richard Geller M.D. https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28832 Wed, 04 Apr 2018 13:51:06 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28832 It would be helpful to get the specifications of the Mayo freezing apparatus and specimen management protocol. Is it published? Is the Mayo equipment commercially available? 60 second turnaround time sounds amazing. Do you ink the specimen margin prior to frozen and cut the inked surface en face? How many sections would a 3x3x3 cm lumpectomy require?

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By: Kelley Schreiber https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28831 Mon, 02 Apr 2018 15:34:13 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28831 In reply to Jerry baldwin.

Thank you for your comment. According to Dr. Keeney, we do provide local “outreach” on a case by case bases. Interestingly it’s all breast cases. At Mayo Rochester we use a freezing microtome. Other pathology practices use the cryostat. The methodology of the freezing microtome allows faster tissue processing without frozen section artifact. It also allows cutting micro-sections of difficult tissue like fat. Freezing microtomes do have limited usage in research settings. We evaluated several when our older microtomes broke down. They all had a different cutting motion from the Mayo microtome. We were not able to adapt them into our clinical practice. We worked with Mayo engineering to develop/modify the freezing microtome we currently use. We provide frozen section outreach for a local hospital on many of their breast cases.

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By: Jerry baldwin https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28816 Thu, 29 Mar 2018 18:41:26 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28816 I enjoyed the article, however do the mayo pathologists do frozen sections on breast cases done on outreach? Probably not . I think your article is little remiss by not explaining the cryostat used at mayo is different than used in the rest of the country and elsewhere. Conventional commercially available cryostats do not cool the fat tissue enough to provide an acceptable slide to interpret accurately.

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By: Dwight Oxley https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28814 Thu, 29 Mar 2018 16:28:07 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28814 Superb historical summary of an overlooked topic.

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By: Dwight Oxley https://news.mayocliniclabs.com/2018/03/27/frozen-and-on-time-rapid-margin-assessment-helps-prevent-repeat-surgeries/#comment-28813 Thu, 29 Mar 2018 16:27:21 +0000 https://news.mayocliniclabs.com/?p=41405#comment-28813 Superb article.

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