The underlying causes of erythrocytosis (high hemoglobin/hematoctrit) have been progressively elucidated in recent years. The identification of the underlying causes has assumed greater importance with the identification of the JAK2 V617 mutation found in polycythemia vera and other myeloproliferative neoplasms.


Image of James Hoyer, M.D.

James Hoyer, M.D.
Consultant, Hematopathology
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science
Co-Director, Metabolic Hematology Laboratory
Mayo Clinic

Learning Objectives

  • Outline the causes of both hereditary and acquired erythrocytosis.
  • Focus on causes of hereditary erythrocytosis and their pathogenesis.
  • Discuss methods that are available to diagnose these disorders.
  • Present an algorithm that can aid in the workup of these patients.
  • Present a series of cases for illustration.

Intended Audience

This webinar is designed for health care professionals who treat patients with hereditary erythrocytosis, including hematopathologists, hematologists, physician assistants, nurse practitioners, and genetic counselors.

Level of instruction


Faculty Disclosure

Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty members also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentations. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentations.

National Physician Payment Transparency Program

Mayo Medical Laboratories is not an applicable manufacturer or applicable group purchasing organization (GPO). (GPOs, per the Centers for Medicare & Medicaid Services, and this program do not trigger any reporting requirements pursuant to Open Payments [Sunshine Act] legislation.)

Note: Credit is not offered for this Specialty Testing webinar.

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This post was developed by our Education and Technical Publications Team.