Genetics Archives - Insights

Cultivating a comprehensive test menu for organ transplant patients

Chris Bahnsen — Fri, 30 Jan 2026 14:00:00 +0000

Viral and pharmacogenomic testing help clinicians detect infection early, tailor immunosuppression, and improve long-term outcomes for organ transplant recipients.

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Pharmacogenomics: Why is everyone talking about DPYD?

MCL Education — Thu, 16 Oct 2025 10:00:00 +0000

The rapidly evolving field of pharmacogenomics, the DPYD gene and its significance in oncology.

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Whole Exome Sequencing Reflex Test Offers Cost-Effective Diagnosis: Cherisse Marcou, Ph.D., and Kristen Rasmussen, M.S., CGC

Barbara J. Toman — Tue, 02 Sep 2025 13:00:00 +0000

Cherisse Marcou, Ph.D., and Kristen Rasmussen, M.S., CGC, explain how Mayo Clinic Laboratories' WESPR whole exome sequencing reflex test provides cost-effective diagnosis of complex genetic conditions. Using samples and data from previous targeted gene panels, WESPR's wider net can identify undetected genetic variants.

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Advancing Immunosuppressive Therapy in Solid Organ Transplantation: Integrating Pharmacogenomics, Therapeutic Drug Monitoring, and Precision Medicine

MCL Education — Fri, 06 Jun 2025 10:00:00 +0000

PACE/State of FL - The critical role of pharmacogenomics and therapeutic drug monitoring (TDM) in managing immunosuppressive therapy for solid organ transplant recipients.

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A journey to diagnosis: One patient’s story of resilience and hope

jgilligan1 — Mon, 05 May 2025 13:00:00 +0000

For many, the path to a correct diagnosis can be long and filled with uncertainty. This story highlights the resilience and determination of one patient who navigated a complex medical journey to find answers and hope at Mayo Clinic. The patient asked to remain anonymous for personal privacy reasons.

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Cytology Specimen Utilization: A Proven Approach to Genetic Sequencing

MCL Education — Wed, 09 Apr 2025 14:00:00 +0000

PACE/State of FL - The role of cytology specimens in molecular genetic testing, emphasizing their effectiveness in identifying biomarkers critical for targeted therapies in patients with cancer.

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Comprehensive Genetic Test Guides Prescribing of a Transplant Anti-Rejection Drug: Jessica Wright, Pharm.D., BCACP

Barbara J. Toman — Tue, 08 Apr 2025 13:00:00 +0000

Jessica Wright, Pharm.D., BCACP, explains how Mayo Clinic Laboratories' 3A5Q test helps determine initial tacrolimus doses for individuals after non-liver organ transplants. Optimal tacrolimus levels are one of the important factors in survival of the transplanted organ.

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Innovative SORD test provides clarity for two young patients: Justin Fugelsang and Zach Pedowitz

Chris Bahnsen — Mon, 13 Jan 2025 14:00:00 +0000

Justin Fugelsang and Zach Pedowitz have never met. Yet both young men were diagnosed with a rare form of Charcot-Marie-Tooth disease, called sorbitol dehydrogenase (SORD) deficiency, and both found clarity through Mayo Clinic Laboratories' innovative SORD testing. Their journeys inspire resilience, as Justin has channeled his emotions into guitar playing, and Zach has embraced educational leadership.

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Making Informed Decisions About Genetic Testing: Carrie Lahner, M.S., CGC, and April Studinski Jones, M.S., CGC

Jessie Fenske — Thu, 14 Nov 2024 14:00:00 +0000

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by genetic counselors Carrie Lahner, M.S., CGC, and April Studinski Jones, M.S., CGC, to discuss how family medical history can inform genetic testing strategies.

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Genetic Tests Identify Risk of Irinotecan-Induced Toxicity: John Logan Black, M.D.

Barbara J. Toman — Tue, 12 Nov 2024 14:00:00 +0000

John Logan Black, M.D., explains how Mayo Clinic Laboratories' UGT1A1 tests (Mayo IDs: U1A1Q and UGTFZ) identify genetic variants that increase the risk of potentially life-threatening reactions to irinotecan, a chemotherapy agent.

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