Lyme disease is a tick-borne illness that is endemic in certain areas of the United States, including the Northeast and Upper Midwest. In several situations, laboratory testing is not recommended. However, laboratory diagnosis of Lyme disease is most commonly achieved by serologic testing, which should be limited to those persons with an appropriate exposure history and objective clinical findings. When serology is ordered, testing should be performed using the two-step approach as recommended by the CDC.

By Kelley Luedke • May 1, 2013

COLA, a leading laboratory accreditor, announced that it is expanding its educational offerings by collaborating with Mayo Medical Laboratories, a global reference laboratory operating within Mayo Clinic’s Department of Laboratory Medicine and Pathology. Under the agreement, COLA is now providing a convenient link to Mayo Medical Laboratories’ test utilization website directly from and the accreditor’s educational portal, Read more for full details.

By mayocliniclabs • April 15, 2013

Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy. The guidelines are published in the current issue of the journal Mayo Clinic Proceedings and represent a consensus opinion of hematologists at Mayo Clinic Cancer Center sites in Minnesota, Florida and Arizona.

By mayocliniclabs • April 10, 2013

Mayo Clinic gastroenterologist and celiac disease expert Joseph Murray, M.D., discusses a recent article published in the Journal of Agricultural and Food Chemistry that studied the possibility that increased gluten content in wheat from wheat breeding has led to the increase of celiac disease seen during the latter part of the twentieth century.

By Andy Tofilon • April 2, 2013

Mayo Laboratory Inquiry, the customer service center for Mayo Medical Laboratories, has recently been certified as a 2013 Center of Excellence by BenchmarkPortal, a global leader in the contact center industry, for the second year in a row.

By mayocliniclabs • March 7, 2013

Rapid City Regional Hospital (RCRH), a 417 bed hospital located in the Black Hills of South Dakota, identified a marked increase in the use of blood products and associated costs at a time when blood components were in short supply. After hearing James Stubbs, M.D., medical director of transfusion medicine at Mayo Clinic Rochester, speak about best practices and the financial impact of transfusion medicine costs, RCRH implemented a blood management program to decrease blood usage.

By Kelley Luedke • March 1, 2013

Mayo Clinic and Silicon Valley Biosystems (SV Bio) today announced a strategic collaboration for whole genome diagnostics and interpretation at the Mayo Clinic Center for Individualized Medicine and Mayo Medical Laboratories. This strategic collaboration unites SV Bio’s proprietary genome interpretation solution with Mayo Clinic’s growing genome reference library and its commitment to individualized medicine, and will increase accessibility and clinical utility of next-generation sequencing for patients.

By mayocliniclabs • January 22, 2013

A common ordering error among molecular tests is ordering a diagnostic test when a known-mutation test is indicated, and vice versa. Mayo Medical Laboratories offers tests to either diagnose the disease or determine if a previously identified genetic abnormality is present in a family member.

By Kelley Luedke • January 2, 2013

Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are nonspecific tests for acute inflammatory processes. Studies have demonstrated equivalent performance of ESR and CRP in a majority of patient populations, with the exception of patients with temporal arteritis and polymyalgia rheumatica. Mayo Clinic identified and evaluated patient populations where ESR and CRP were ordered concurrently to determine whether there was any added value to ordering both tests.

By Kelley Luedke • November 1, 2012

A recent review of Mayo Medical Laboratories test requests revealed an increase in orders for erythrocyte magnesium (Mg-RBC) and erythrocyte zinc (Zn-RBC). Discussions with health care providers ordering these tests indicate that Mg-RBC is used almost solely to assess nutritional status in diabetic patients. In this spotlight, Mayo Medical Laboratories investigated the utility of red blood cell testing.

By Kelley Luedke • September 1, 2012

Today’s clinical laboratory can offer a wide expanse of various genetic tests that can be requested by a clinician. The large repertoire of genetic testing services offered by Mayo Medical Laboratories can make selecting the appropriate test complicated. Mayo Clinic’s laboratory genetic counselors are available to help physicians select the most appropriate tests for their patients and reduce unnecessary testing.

By Kelley Luedke • May 1, 2012