Microbiology / Infectious Disease
According to data from the Mayo Clinic Clinical Virology Laboratory, influenza activity has hit its peak in Rochester, Minnesota, and is widespread in 43 states, including Minnesota, Iowa, Wisconsin and South Dakota. The most common subtype is H3N2, which appears to be responding well to antivirals.
Bordetella pertussis is the highly contagious etiological agent of pertussis or whooping cough. Bordetella parapertussis causes a similar but generally less severe illness. Diagnosis of pertussis is based on having a high clinical index of suspicion for the infection, along with confirmation by laboratory testing.
In a recent article in AACC, Elitza Theel, Ph.D., Director of the Infectious Disease Serology Laboratory at Mayo Clinic, and Matt Binnicker, Ph.D., Director of the Clinical Virology Laboratory in the Division of Clinical Microbiology at Mayo Clinic, review current syphilis assays and explain how laboratories can implement a new algorithm and advise clinicians.
Robin Patel, M.D., recently reviewed MALDI-TOF MS in Clinical Chemistry, providing a historical perspective on this new technology. MALDI-TOF MS is used as a tool for rapid, accurate, and cost-effective identification of cultured bacteria and fungi in clinical microbiology.
Central nervous system infection due to herpes simplex virus (HSV) is a medical emergency and requires a rapid diagnosis and initiation of therapy. A recent study published in the Journal of Clinical Microbiology by Matthew Binnicker, Ph.D., Mark Espy, and Cole Irish, compared a routine real-time PCR assay for HSV type 1 (HSV-1) and HSV-2 to a recently FDA-approved direct PCR assay using cerebrospinal fluid samples.
Based on extensive consultation with experts in every area of our laboratory practice and an exhaustive review of our processes and procedures, Mayo Medical Laboratories will NOT ACCEPT specimens from patients suspected of having Ebola Virus Disease. Read this post to learn more about the three main reasons for this decision.
As of Aug. 22, there have been over 2600 suspected or confirmed cases of Ebola hemorrhagic fever. Of these cases, two adult United States nationals were admitted to Emory University Hospital in Atlanta, GA during the first week of August 2014 for treatment. To discuss their treatment, doctors of Emory Hospital authored the article, "Laboratory Test Support for Ebola Patients Within a High-Containment Facility," in American Society for Clinical Pathology's Lab Medicine Journal.
Advanced Biological Laboratories, S.A, and Mayo Medical Laboratories have announced a collaboration agreement to develop a deep-sequencing pipeline for novel diagnostic laboratory-developed tests.
The new Histoplasma Antigen, Urine test is now available to the Mayo Clinic practice and Mayo Medical Laboratories clients. This test should be ordered in individuals suspected to be infected with Histoplasma capsulatum.
Mayo Medical Laboratories would like to remind its clients that samples should not be submitted to any reference laboratory for any type of testing if a patient is being investigated for a viral hemorrhagic fever (e.g., Ebola virus) or Middle East Respiratory Syndrome coronavirus. Testing for these infectious diseases must be coordinated with local public health authorities.
Historically, only certain pockets of the United States posed a risk for tick-borne disease, such as Lyme disease, anaplasmosis, babesiosis, ehrlichiosis, and Rocky Mountain spotted fever. However, with recent reports of increase in confirmed cases throughout multiple areas, it's clear the geographic range of ticks is expanding and large areas of the population are now at risk.
The Centers for Disease Control and Prevention (CDC) has announced that the first case of locally acquired mosquito-borne chikungunya virus in the United States has been confirmed in a Florida man.
In May, the U.S. Centers for Disease Control and Prevention (CDC) confirmed two cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the United States. To ensure health care providers know how to handle suspected cases, the Mayo Clinic Virology Laboratory has put together a list of six things providers need to know.