Microbiology / Infectious Disease
Preliminary estimates released by the Centers for Disease Control and Prevention at the 2013 International Conference on Lyme Borreliosis and Other Tick-Borne Diseases indicate that the number of Americans diagnosed with Lyme disease each year is around 300,000.
In the United States, major tick-borne diseases include Lyme disease, anaplasmosis, babesiosis, ehrlichiosis, and Rocky Mountain spotted fever. Historically, only certain pockets of the United States posed a risk for tick-borne disease. However, the geographic range of ticks has expanded and large areas of the population are now at risk. Because of this increased risk, it is important that physicians recognize who to test, when to test, and what test to use.
Pyrazinamide is one of the four first-line agents used to treat Mycobacterium tuberculosisinfections. It is a unique agent in regards to susceptibility testing because it requires testing under acidic conditions, and it is well documented in relevant literature that current broth methods tend to overcall resistance to this agent.
Lyme disease is a tick-borne illness that is endemic in certain areas of the United States, including the Northeast and Upper Midwest. In several situations, laboratory testing is not recommended. However, laboratory diagnosis of Lyme disease is most commonly achieved by serologic testing, which should be limited to those persons with an appropriate exposure history and objective clinical findings. When serology is ordered, testing should be performed using the two-step approach as recommended by the CDC.
In mid-March, the Centers for Disease Control and Prevention and the World Health Organization announced the presence of a novel coronavirus in the Arabian Peninsula and the United Kingdom. In this video, Matthew Binnicker, Ph.D., laboratory director of the Mayo Clinic Virology Laboratory, outlines key things health care providers should know about this coronavirus and proper testing protocol.
Heart valve infections are one of the complications of implanted cardiac devices. Mayo Clinic's infectious disease experts are leaders in finding solutions to this problem, and their research has already changed medical practice and helped heart patients everywhere.
Dimorphic fungi cause several common diseases including histoplasmosis, blastomycosis, and coccidioidomycosis. In this 5-part “Hot Topic,” Glenn Roberts, Ph.D., discusses the distribution and ecology of these fungi, as well as their pathogenesis and cultural characteristics.
Glenn Roberts, Ph.D., a retired Mayo Clinic mycologist, was featured in an article in the Scientific American regarding the recent fungal meningitis outbreak.
It might seem like ticks are a spring and summer problem, but it’s also important to take steps to prevent tick bites when you are outside on mild fall and winter days, especially if you live in the Midwest or Northeast.
Mayo Medical Laboratories has received a number of questions from laboratories around the country in regards to testing for fungal meningitis. The key message is that your organization should continue to utilize your normal approach for fungal meningitis. For your reference, we have created an infographic with some key points from Mayo Clinic microbiologists.
In this 11-part “Hot Topic” series, Glenn Roberts, Ph.D., addresses one or more genus or group in direct microscopic examination of fungi in clinical specimens that relies on both bright-field and phase-contrast microscopy, as well as multiple stains to optimize visualization of the organism.
In this 2-part “Hot Topic,” Glenn Roberts, Ph.D., shares his lifetime of experience to assist you in differentiating Dermatophyte organisms under consideration in your patient’s differential diagnosis.
In the April 22 edition of US News & World Report, Bobbi Pritt, M.D., director of Mayo Clinic's Clinical Parasitology and Virology Laboratories, observes that patients have been showing up a month or so early this year with tick-borne illnesses such as Lyme disease, anaplasmosis and babesiosis, due to the early arrival of spring.