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WHAT IS PHARMACOGENOMICS, AND WHY IS IT IMPORTANT?

The drugs available today to treat cardiovascular disease are powerful agents that work as intended in most patients. Yet, in some people, a particular drug at the standard dose might not work well enough or may even trigger a serious adverse reaction. This can be due to genetic causes, which often play an important role in a patient’s predisposition to experiencing adverse drug reactions or therapeutic failure. The science of pharmacogenomics studies how a patient’s specific DNA sequences influence his or her response to medications.

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By using a patient’s unique genetic makeup as a factor when prescribing a drug, physicians are able to ensure the right drug at the right dose at the right time to maximize treatment effectiveness while avoiding potentially life-threatening side effects.

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