Oncology - MayoComplete Archives - Insights

New assay can detect fusions in 1,445 genes across wide range of tumors

Chris Bahnsen — Mon, 20 Apr 2026 13:00:00 +0000

New wtRNA-seq test detects fusions in 1,445 genes with high accuracy, improving cancer diagnosis, treatment decisions, and clinical trial eligibility.

The post New assay can detect fusions in 1,445 genes across wide range of tumors appeared first on Insights.

Rare kidney disease diagnostic advances recognized for clinical impact

Jessie Fenske — Thu, 02 Apr 2026 13:00:00 +0000

Research improves the diagnosis of rare Birt-Hogg-Dubé syndrome, closing genetic testing gaps, guiding care, and earning recognition as a top paper.

The post Rare kidney disease diagnostic advances recognized for clinical impact appeared first on Insights.

Whole transcriptome RNA sequencing

Robin Huiras-Carlson — Tue, 03 Feb 2026 14:00:00 +0000

Learn more about how Mayo Clinic Laboratories approach to whole transcriptome RNA sequencing provides the most comprehensive detection of gene fusions in solid tumors through use of next-generation sequencing to identify fusions in 1,445 genes.

The post Whole transcriptome RNA sequencing appeared first on Insights.

Dr. Dong Chen and Dr. Sounak Gupta join Becker’s Healthcare Podcast to discuss molecular testing in cancer care

jgilligan1 — Tue, 29 Oct 2024 01:00:00 +0000

Dr. Dong Chen and Dr. Sounak Gupta joined the “Becker’s Healthcare Podcast” to discuss the molecular testing space and its important role in personalized cancer treatment. Dr. Chen and Dr. Gupta highlighted the importance of selecting the right molecular tests for patients, the impact of genetic testing on cancer diagnosis and treatment, and how Mayo Clinic Laboratories is helping physicians make informed decisions for the best patient outcomes.

The post Dr. Dong Chen and Dr. Sounak Gupta join Becker’s Healthcare Podcast to discuss molecular testing in cancer care appeared first on Insights.

Advanced Diagnostics Laboratory helps improve the way oncologists treat patients through development of the Mayo Complete Solid Tumor Panel

Chris Bahnsen — Wed, 25 Sep 2024 13:00:00 +0000

Founded in 2017, Mayo Clinic's Advanced Diagnostics Laboratory is a visionary space. In 2021, the lab developed the Mayo Complete Solid Tumor Panel, a clinically validated assay that analyzes 515 genes using next-generation sequencing. This multiple test panel, the first of its kind at Mayo, aids in selecting targeted therapies, diagnosing tumor types, and predicting prognosis, significantly improving patient care.

The post Advanced Diagnostics Laboratory helps improve the way oncologists treat patients through development of the Mayo Complete Solid Tumor Panel appeared first on Insights.

Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S.

Barbara J. Toman — Tue, 21 May 2024 13:00:00 +0000

Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S., explain how Mayo Clinic Laboratories' enhanced MayoComplete Solid Tumor Panel better profiles tumor genetics. Defining tumor pathogenesis can guide targeted cancer therapy.

The post Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S. appeared first on Insights.

Revolutionizing Endometrial Cancer Diagnostics

Nicole Holman — Wed, 20 Dec 2023 14:00:00 +0000

Endometrial cancer affects thousands annually and ranks as the fourth most common cancer among women in the United States. At the forefront of innovative discoveries in endometrial cancer diagnostics are Mayo Clinic's Department of Laboratory Medicine and Pathology consultants. Sounak Gupta, M.B.B.S., Ph.D., vice chair of Oncology Practice for the Division of Laboratory Genetics and Genomics; Maryam Shahi, M.D., senior consultant for Anatomic Pathology; and Andrea Mariani, M.D., M.S., division chair of Gynecologic Surgery, explore the critical significance of molecular profiling and collaborative efforts driving these innovations, highlighting Mayo Clinic’s revolutionary influence on patient care.

The post Revolutionizing Endometrial Cancer Diagnostics appeared first on Insights.

Breast cancer panel halves turnaround time: Wei Shen, Ph.D.

Barbara J. Toman — Tue, 25 Jul 2023 13:00:00 +0000

In this test-specific episode of the "Answers From the Lab" podcast, Wei Shen, Ph.D., explains how Mayo Clinic Laboratories' new breast cancer panel provides rapid results to guide critical decisions about treatment and screening.

The post Breast cancer panel halves turnaround time: Wei Shen, Ph.D. appeared first on Insights.

Urologic panels provide focused cancer testing: Sounak Gupta, M.B.B.S., Ph.D.

Barbara J. Toman — Tue, 11 Jul 2023 13:00:00 +0000

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' urologic panels efficiently inform prognosis and individualized cancer treatment. The carefully curated panels fill the void between single gene assays and large NGS panels.

The post Urologic panels provide focused cancer testing: Sounak Gupta, M.B.B.S., Ph.D. appeared first on Insights.

Chromosomal microarray better informs brain tumor diagnosis

Barbara J. Toman — Tue, 21 Feb 2023 14:00:00 +0000

Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor analysis compared with other test methods.

The post Chromosomal microarray better informs brain tumor diagnosis appeared first on Insights.