Chromosomal microarray better informs brain tumor diagnosis
Answers from the Lab
Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. In this test-specific episode of the "Answers From the Lab" podcast, Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor analysis compared with other test methods.
"The array test covers all the possibilities," Dr. Jenkins says. "It easily finds the various mutations that are essential for diagnosis and prognosis."
He notes that the chromosomal microarray is more accurate than fluorescence in situ hybridization (FISH), and requires less tumor content than methylation assay.
Each microarray is analyzed by an experienced Mayo Clinic pathologist. "We use our specialist knowledge about brain tumors and what we see in the microarray to generate a meaningful report that can guide a care plan for these complex brain tumors," Dr. Jenkins says.
Listen to learn more about Mayo Clinic Laboratories' chromosomal microarray assay.
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Specimen Required (submit only 1 of the following specimens):
Ordering Guidance: This test is not performed on fresh tissue specimens. If testing is needed for fresh tissue specimens, order CMAT / Chromosomal Microarray, Tumor, Fresh or Frozen using Affymetrix Cytoscan HD.
Necessary Information: A reason for testing and pathology report are required for testing to be performed. Send information with specimen. Acceptable pathology reports include working drafts, preliminary pathology or surgical pathology reports.
Analytic time: 10 to 21 days
Days performed: Monday through Friday
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Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor analysis compared with other test methods.