Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 8

By Kelley Luedke • October 8, 2018

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The Research Roundup provides an overview of the past week’s research from Mayo Medical Laboratories consultants, including featured abstracts and complete list of published studies and reviews.

Featured Abstract

Radical Versus Partial Nephrectomy for cT1 Renal Cell Carcinoma

Nephron-sparing surgery is the preferred surgical management of cT1 renal masses, but observational and randomized data conflict regarding a survival benefit. Mayo Clinic researchers conducted a study to examine the associations of radical nephrectomy versus partial nephrectomy with oncologic and nononcologic outcomes. A total of 2459 adults were treated with radical nephrectomy or partial nephrectomy between 1990 and 2011 for a unilateral, sporadic, cT1, M0 solid renal mass. The study results found that although radical nephrectomy was associated with an increased risk of chronic kidney disease compared with partial nephrectomy, it was not associated with a statistically significant difference in cancer-specific mortality or all-cause mortality among patients with cT1 renal cell carcinoma. The study was published in European Urology.

Published to PubMed This Week

• • • • • Smouldering Mastocytosis: Survival Comparisons with Indolent and Aggressive Mastocytosis
          American Journal of Hematology
        • Limitations and Confusing Aspects of Diagnostic Testing for Neurologic Lyme Disease in the United States
          Journal of Clinical Microbiology
        • Impact of Changes to Donor Hemoglobin Criteria on the Rate of Donor Deferral
          Transfusion
        • Use of Mate-Pair Sequencing (MPseq) to Characterize a Complex Cryptic BCR/ABL1 Rearrangement Observed in a Newly Diagnosed Case of Chronic Myeloid Leukemia
          Human Pathology
        • Elderly Acute Lymphoblastic Leukemia: A Mayo Clinic Study of 124 Patients
          Leukemia & Lymphoma
        • Diagnostic Methods for Prosthetic Joint Infection in Korea
          Infection & Chemotherapy

Kelley Luedke

Kelley Luedke is a Marketing Channel Manager at Mayo Clinic Laboratories. She is the principle editor and writer of Insights and leads social media and direct marketing strategy. Kelley has worked at Mayo Clinic since 2013. Outside of work, you can find Kelley running, traveling, playing with her kitty, and exploring new foods.