Mayo Clinic Laboratory and Pathology Research Roundup: July 22
Share this:
The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing.
Pancreatic cystic lesions (PCLs) may be precancerous. Those likely to harbor high-grade dysplasia (HGD) or pancreatic cancer (PC) are targets for surgical resection. Current algorithms to predict advanced neoplasia (HGD/PC) in PCLs lack diagnostic accuracy. In pancreatic tissue and cyst fluid (CF) from PCLs, we sought to identify and validate novel methylated DNA markers (MDMs) that discriminate HGD/PC from low-grade dysplasia (LGD) or no dysplasia (ND).
Published to PubMed This Week
- Integration of Machine Learning and Mechanistic Models Accurately Predicts Variation in Cell Density of Glioblastoma Using Multiparametric MRI.
Scientific Reports - OLIG2 Is a Marker of the Fusion Protein-Driven Neurodevelopmental Transcriptional Signature in Alveolar Rhabdomyosarcoma.
Human Pathology - Incidence of Succinate Dehydrogenase and Fumarate Hydratase-Deficient Renal Cell Carcinoma Based on Immunohistochemical Screening with SDHA/SDHB and FH/2SC.
Human Pathology - What Are We REALLY Looking for in a Letter of Recommendation?
Journal of Surgical Education - Phosphaturic Mesenchymal Tumors: A Review and Update.
Seminars in Diagnostic Pathology - Assessment of The Bethesda System for Reporting Thyroid Cytopathology.
American Journal of Clinical Pathology - Immunohistochemical and Ultrastructural Features of Hepatocellular Cytoplasmic Globules in Venous Outflow Impairment.
American Journal of Clinical Pathology - A Fatal Case of Disseminated Microsporidiosis Due to Anncaliia algerae in a Renal and Pancreas Allograft Recipient.
Open Forum Infectious Disease
