The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Patients with MS (n=16) and controls (n=80) matched for age, sex and APOE ε4 status from the population-based Mayo Clinic Study of Aging who underwent PiB PET imaging were studied. Of these individuals, 12 patients with MS and 60 matching controls also underwent AV1451 tau PET. Cortical PiB and AV1451 standard uptake value ratios (SUVr) from the entire cortex and previously determined Alzheimer's disease (AD) signature regions in the same population were calculated for group comparisons and testing for associations with age. Via Annals of Neurology.