Mayo Clinic Laboratory and Pathology Research Roundup: March 23

By Samantha Rossi • March 23, 2020

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Analysis of Tumor Microenvironmental Features to Refine Prognosis by T, N Risk Group in Patients with Stage III Colon Cancer (NCCTG N0147) (Alliance).

Tumor-infiltrating lymphocytes (TILs), tumor budding, and micropapillary architecture may influence tumor growth and metastatic potential, thereby enhancing prognostic stratification. We analyzed these features and their relative contribution to overall outcome and in low (T1-3 N1) and high (T4 and/or N2) risk groups that are used to inform the duration of adjuvant chemotherapy in patients with resected stage III colon cancers. Via Annals of Oncology.

Read more.

Published to PubMed This Week

• An Institutional Approach to Managing the Opioid Crisis.
  Mayo Clinic Proceedings
• Monozygotic twins discordant for congenital adrenal hyperplasia due to mosaicism.
  European Journal of Endocrinology
• Identifying human leukocyte antigen (HLA)-compatible platelets using the Matchmaker programme in alloimmunised platelet-refractory patients.
  Transfusion Medicine
• Impact of marrow blasts percentage on high-grade myelodysplastic syndrome assessed using revised international prognostic scoring system.
  Annals of Hematology
• Development of biopsy-proven giant cell arteritis in a patient with dermatomyositis on methotrexate: comment on the article by Monti et al.
  Clinical and Experimental Rheumatology
• The Mayo Clinic Hospital Mortality Reduction Project: Description and Results.
  Journal of Healthcare Management
• Outcomes of Onyx® Embolization of Type II Endoleaks after Endovascular Repair of Abdominal Aortic Aneurysms.
  Annals of Vascular Surgery
• Characteristics of patients with myelodysplastic syndrome with balanced translocations.
  British Journal of Haematology
• A digital health weight-loss intervention in severe obesity.
  Digital Health

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.