Mayo Clinic laboratory and pathology research roundup: May 4

By Samantha Rossi • May 4, 2021

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Positive predictive value of myelin oligodendrocyte glycoprotein autoantibody testing.

This diagnostic study was conducted over 2 years, from January 1, 2018, through December 31, 2019. Patients in the Mayo Clinic who were consecutively tested for MOG-IgG1 by live cell-based flow cytometry during their diagnostic workup were included. Patients without research authorization were excluded. Via JAMA Neurology.

Read more.

Published to PubMed This Week

• Clinical utility of striational antibodies in paraneoplastic and myasthenia gravis paraneoplastic panels.
  Neurology
• Detection of pathogenic bacteria from septic patients using 16S rRNA gene targeted metagenomic sequencing.
  Clinical Infectious Disease
• Mutations and thrombosis in essential thrombocythemia.
  Blood Cancer Journal
• COVID-19 infection in solid organ transplant recipients after SARS-CoV-2 vaccination.
  American Journal of Transplant
• PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer.
  JCI Insights
• Clinical utility of antiretinal antibody testing.
  JAMA Ophthalmology
• Young platelet millionaires with essential thrombocythemia.
  American Journal of Hematology
• Assessment of fixed-duration therapies for treatment-naïve waldenström macroglobulinemia.
  American Journal of Hematology
• Acute myeloid leukemia after age 70 years: A retrospective comparison of survival following treatment with intensive versus HMA ± venetoclax chemotherapy.
  American Journal of Hematology
• Clinical, molecular, and prognostic comparisons between CCUS and lower-risk MDS: a study of 187 molecularly annotated patients.
  Blood Advances

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.