Mayo Clinic Laboratory and pathology research roundup: December 21
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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Learning through a Pandemic: The current state of knowledge on COVID-19 and cancer.
The ongoing COVID-19 pandemic has left patients with current or past history of cancer facing disparate consequences at every stage of the cancer trajectory. This comprehensive review offers a landscape analysis of the current state of the literature on COVID-19 and cancer including the immune response to COVID-19, risk factors for severe disease, and impact of anticancer therapies. We also review the latest data on treatment of COVID-19 and vaccination safety and efficacy in patients with cancer, as well as impact of the pandemic on cancer care, including the urgent need for rapid evidence generation and real-world study designs.
Published to PubMed This Week
- Outcomes in primary cutaneous diffuse large B-cell lymphoma, leg type.
Hematological Oncology - Implications of MYC rearrangements in newly diagnosed multiple myeloma.
Clinical Cancer Research - Sorbitol is a severity biomarker for PMM2-CDG with therapeutic implications.
Annals of Neurology - Interpretation and reporting of large regions of homozygosity and suspected consanguinity/uniparental disomy, 2021 revision: A technical standard of the American college of medical genetics and genomics (ACMG).
Genetics in Medicine - Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants.
Genetics in Medicine - Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology.
Journal of Neuroinflammation - Correction to: Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group.
Modern Pathology - Cardiopulmonary resuscitation training to improve out-of-hospital cardiac arrest survival: addressing potential health inequalities.
European Journal of Preventive Cardiology - Detection of plasma cell disorders by mass spectrometry: A comprehensive review of 19,523 cases.
Mayo Clinic Proceedings - CSF kappa free light chains: Cutoff validation for diagnosing multiple sclerosis.
Mayo Clinic Proceedings
