Mayo Clinic Laboratory and pathology research roundup: February 1

By Chantell Canfield • February 1, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Androgen deprivation therapy use and duration with definitive radiotherapy for localised prostate cancer: an individual patient data meta-analysis.

Randomised trials have investigated various androgen deprivation therapy (ADT) intensification strategies in men receiving radiotherapy for the treatment of prostate cancer. This individual patient data meta-analysis of relevant randomised trials aimed to quantify the benefit of these interventions in aggregate and in clinically relevant subgroups.

Read more.

Published to PubMed This Week

• Access to and safety of COVID-19 convalescent plasma in the United States Expanded Access Program: A national registry study.
  PLoS Medicine
• Molecular markers demonstrate diagnostic and prognostic value in the evaluation of myelodysplastic syndromes in cytopenia patients.
  Blood Cancer Journal
• Myeloid malignancies in cancer patients treated with poly(ADP-ribose) polymerase (PARP) inhibitors: a case series.
  Blood Cancer Journal
• Residency program directors' perceptions about the impact of the American board of anesthesiology's objective structured clinical examination.
  Journal of Clinical Anesthesiology
• Inflammatory cells in nephrectomy tissue from patients without and with a history of urinary stone disease.
  Clinical Journal of the American Society of Nephrology
• Vax-plasma in patients with refractory COVID-19.
  Mayo Clinic Proceedings
• Automated quantification of levels of breast terminal duct lobular (TDLU) involution using deep learning.
  NPJ Breast Cancer
• CDK5RAP3, a new BRCA2 partner that regulates DNA repair, is associated with breast cancer survival.
  Cancers
• The alliance AMBUSH trial: rationale and design.
  Cancers
• Composite classic hodgkin lymphoma and follicular lymphoma: A clinicopathologic study of 22 cases with review of 27 additional cases in the literature.
  The American Journal of Surgical Pathology

Chantell Canfield

Chantell Canfield is a web content coordinator for Mayo Clinic Laboratories. She began working for Mayo Clinic in 2021.