Mayo Clinic Laboratory and pathology research roundup: May 10

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.
Mitral valve prolapse (MVP) is a common valvular heart disease with a prevalence of >2% in the general adult population. Despite this high incidence, there is a limited understanding of the molecular mechanism of this disease, and no medical therapy is available for this disease.
Published to PubMed This Week
- Overall patient experience with a virtual hybrid hospital at home program.
SAGE open medicine - MRI enhancement patterns in 28 cases of clival chordomas.
Journal of clinical neuroscience - Letter to the editor regarding "fifth generation cellular networks and neurosurgery: A narrative review".
World neurosurgery - Lacrimal gland involvement in a patient with sarcoidosis.
Cleveland Clinic journal of medicine - Clonal compositions involving epigenetic regulator and splicing mutations in CHIP, CCUS, MDS, and CMML.
Leukemia research - Apparent coexistence of ETV6::RUNX1 and KMT2A::MLLT3 fusions due to a nonproductive KMT2A rearrangement in B-ALL.
Leukemia and lymphoma - A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer.
Cancer chemotherapy and pharmacology - Clinical and laboratory profiles of SARS-CoV-2 Delta variant compared to pre-Delta variants.
International journal of infectious diseases - Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex-specific and lifestyle factors specific associations.
International journal of cancer - Accessory genomes drive independent spread of carbapenem-resistant klebsiella pneumoniae clonal groups 258 and 307 in Houston, TX.
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