Mayo Clinic Laboratory and pathology research roundup: August 30
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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Kidney biopsy chronicity grading in antineutrophil cytoplasmic antibody-associated vasculitis
Kidney biopsy is valuable for prognostic assessment of renal outcomes in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with glomerulonephritis (AAV-GN) but the impact of chronic changes is not determined. We conducted a retrospective cohort study of myeloperoxidase (MPO)- or proteinase 3 (PR3)-ANCA-positive patients with AAV and active renal disease. We applied the Mayo Clinic Chronicity Score (MCCS) and validated and evaluated its implications on outcome prediction in AAV-GN. Chronic changes on kidney histology independently predict renal function, outcomes and response to treatment in AAV-GN.
Published to PubMed This Week
- Evaluating the significance of pancreatobiliary fish polysomy on prognosis in de novo cholangiocarcinoma
Clinical and translational gastroenterology - Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies
Blood - Dysexecutive Alzheimer's disease with Lewy body disease co-pathology
Current Alzheimer research - Flurofamide prevention and treatment of ureaplasma-induced hyperammonemia
Microbiology spectrum - How do frontline healthcare workers learn from COVID-19 webinars during a pandemic? An online survey study
Hospital practice (1995) - Acinetobacter baumannii genomic sequence-based core genome multilocus sequence typing using Ridom SeqSphere+ and antimicrobial susceptibility prediction in ARESdb
Journal of clinical microbiology - Monkeypox 2022: gearing up for another potential public health crisis
Mayo Clinic proceedings - Outcomes of allogeneic transplant in patients with DDX41 mutated myelodysplastic syndrome and acute myeloid leukemia
Bone marrow transplantation - Operative management of cardiac papillary fibroelastomas
The Journal of thoracic and cardiovascular surgery - Video feedback with error-focused or correct-focused examples in surgical skills distance learning: a randomized trial
Surgery
