Mayo Clinic Laboratory and pathology research roundup: September 27

By Samantha Rossi • September 27, 2022

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Robotics in neurosurgery: current prevalence and future directions

The first instance of a robotic-assisted surgery occurred in neurosurgery; however, it is now more common in other fields such as urology and gynecology. This study aims to characterize the prevalence of robotic surgery among current neurosurgery programs as well as identify trends in clinical trials pertaining to robotic neurosurgery. Each institution's website was analyzed for the mention of a robotic neurosurgery program and procedures. The future potential of robotics in neurosurgery was assessed by searching for current clinical trials pertaining to neurosurgical robotic surgery.

Read more.

Published to PubMed This Week

• Glucocorticoids mediate transcriptome-wide alternative polyadenylation: potential mechanistic and clinical implications
  Clinical and translational science
• CYCLIN K down-regulation induces androgen receptor gene intronic polyadenylation, variant expression and PARP inhibitor vulnerability in castration-resistant prostate cancer
  Proceedings of the National Academy of Sciences of the United States of America
• Quantification of insulin analogs by liquid chromatography-high-resolution mass spectrometry
  Methods in molecular biology (Clifton, N.J.)
• Differentiation of common IGF-1 variants using HRMS COM determination with follow-up MS/MS verification
  Methods in molecular biology (Clifton, NJ.)
• Detection of 13C-mannitol and other saccharides using tandem mass spectrometry for evaluation of intestinal permeability or leaky gut
  Methods in molecular biology (Clifton, N.J.)
• Quantification of parathyroid hormone and its fragments in serum by liquid chromatography-high-resolution mass spectrometry
  Methods in molecular biology (Clifton, N.J.)
• When to think about other Borreliae:: hard tick relapsing fever (Borrelia miyamotoi), Borrelia mayonii, and beyond
  Infectious disease clinics of North America
• Surveillance mammography in older breast cancer survivors: current practice patterns and patient perceptions
  Journal of geriatric oncology
• Refining interpretation of transcutaneous bilirubin measurement in newborns born late preterm
  Pediatrics and neonatology
• Comparison of two free light chain assays: performance of the involved free light chain ratio and implications for diagnosis of multiple myeloma
  Blood cancer journal
• Plastic surgery's obligation to the transgender community
  Plastic and reconstructive surgery. Global open
• Genetic risk of second primary cancer in breast cancer survivors: the multiethnic cohort study
  Cancer research
• Corrigendum: pharmacokinetic assessment of staphylococcal phage K following parenteral and intra-articular administration in rabbits
  Frontiers in pharmacology
• Characterizing M-protein light chain glycosylation via mass spectrometry
  Clinical biochemistry
• Quality control recommendations for RNASeq using FFPE samples based on pre-sequencing lab metrics and post-sequencing bioinformatics metrics
  BMC medical genomics,
• Single nucleotide polymorphism (SNP) array for histologically ambiguous melanocytic tumors: knowns and unknowns
  The Journal of molecular diagnostics : JMD
• Lessons from histopathologic examination of nephrectomy specimens in patients with tuberous sclerosis complex: cysts, angiomyolipomas & renal cell carcinoma
  Human pathology
  

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.