Mayo Clinic Laboratory and pathology research roundup: November 29
By Samantha Rossi • November 29, 2022
The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Ischemia-reperfusion injury (IRI) refers to a syndrome in which tissue damage is further aggravated and organ function further deteriorates when blood flow is restored after a period of tissue ischemia. Acute myocardial infarction, stress ulcer, pancreatitis, intestinal ischemia, intermittent claudication, acute tubular necrosis, postshock liver failure, and multisystem organ failure are all related to reperfusion injury. AMP-activated protein kinase (AMPK) has been identified in multiple catabolic and anabolic signaling pathways.
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Published to PubMed This Week
Optical genome mapping in acute myeloid leukemia: a multicenter evaluation Blood advances Utility of disc space aspirate cell counts and differentials in the diagnosis of native vertebral osteomyelitis Journal of bone and joint infection , 7 The risk of coronavirus disease 2019 (COVID-19) among individuals with monoclonal B cell lymphocytosis Blood cancer journal , 12 Description, validation, and review of a decade of experience with a laboratory-developed PCR test for detection of Mycobacterium tuberculosis complex in pulmonary and extrapulmonary specimens Journal of clinical tuberculosis and other mycobacterial diseases , 29 Metastatic melanoma involving a genetically confirmed angiofibroma of soft tissue: a previously unreported type of tumor-to-tumor metastasis Journal of cutaneous pathology Video commentary & machine learning: tell me what you see, I tell you who you are Journal of surgical education , 79 Simulation as soothsayer: simulated surgical skills MMIs during residency interviews are associated with first year residency performance Journal of surgical education , 79 Course design and learning outcomes of a practical online ergonomics course for surgical residents Journal of surgical education , 79 Problems and solutions: a special issue of gastrointestinal, pancreatic, and liver pathology Human pathology , 129 Primary leptomeningeal lymphoma: clinicopathologic features of 2 rare phenotypes Journal of neuropathology and experimental neurology , 81 Lessons from histopathologic examination of nephrectomy specimens in patients with tuberous sclerosis complex: cysts, angiomyolipomas, and renal cell carcinoma Human pathology , 129 Therapeutic plasma exchange for steroid refractory idiopathic inflammatory myopathies with interstitial lung disease Journal of clinical apheresis Myocarditis and endomyocardial biopsy: achieving consensus diagnosis on hundred cases Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology , 62 Comparison of the BioFire joint infection panel to 16S ribosomal RNA gene-based targeted metagenomic sequencing for testing synovial fluid from patients with knee arthroplasty failure Journal of clinical microbiology Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality eLife , 11 Glucocorticoids unmask silent non-coding genetic risk variants for common diseases Nucleic acids research Development and evaluation of a core genome multilocus sequencing typing (cgMLST) scheme for serratia marcescens molecular surveillance and outbreak investigations Journal of clinical microbiology , 60 Reduced intensity conditioning allogeneic hematopoietic stem cell transplantation in VEXAS syndrome: data from a prospective series of patients American journal of hematology Malignant left ventricular outflow tract obstruction: a reason to operate? JACC. Case reports , 4 Distinctive nested glomoid neoplasm: clinicopathologic analysis of 20 cases of a mesenchymal neoplasm with frequent GLI1 alterations and indolent behavior The American journal of surgical pathology Diarrhea, colonic stenoses and a kinase inhibitor Gastroenterology Changes in glomerular volume, sclerosis, and ischemia at 5 years after kidney transplantation: incidence and correlation with late graft failure Journal of the American Society of Nephrology : JASN Hybrid tumors with perineurioma components: a systematic review of the literature and illustrative case Acta neurochirurgica Targeted metagenomic sequencing-based approach applied to 2146 tissue and body fluid samples in routine clinical practice Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , 75
