Mayo Clinic Laboratory and pathology research roundup: December 20

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Expanding the platelet inventory to mitigate the impact of severe shortages
The platelet collection and distribution system, based on volunteer nonremunerated donors, apheresis platelet collections, and primarily 1-directional distribution of platelets for up to 5-day room temperature storage at hospitals, typically performs well and provides therapeutic support for hundreds of thousands of patients annually. However, direct and indirect effects of the coronavirus disease 2019 pandemic, particularly during the Omicron wave, produced dramatic systemic failures and severe shortages. We propose 4 initiatives to reinforce the existing platelet pipeline and buffer the platelet supply against future unexpected disruptions.
Published to PubMed This Week
- Value of bone marrow examination in determining response to therapy in patients with multiple myeloma in the context of mass spectrometry-based m protein assessment
Leukemia - Erratum: real-world data combined with studies on regulatory B cells for newly diagnosed multiple myeloma from a tertiary referral hospital in south-western China: erratum
Journal of Cancer, 13 - Progressive brain atrophy and severe neurodevelopmental phenotype in siblings with biallelic COASY variants
American journal of medical genetics. Part A - A second case of liraglutide-type localised amyloidosis
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - Clinical and prognostic impact of STAG2 mutations in myeloid neoplasms: the Mayo Clinic Experience
Blood advances - Research opportunities in the treatment of mitral valve prolapse: JACC expert panel
Journal of the American College of Cardiology, 80