Mayo Clinic Laboratory and pathology research roundup: March 14

By Chantell Canfield • March 14, 2023

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Novel through-the-scope suture closure of colonic Endoscopic Mucosal resection defects.

Large colon polyps removed by endoscopic mucosal resection (EMR) can be complicated by delayed bleeding. Prophylactic defect clip closure can reduce post-EMR bleeding. Larger defects can be challenging to close using through-the-scope clips (TTSCs) and proximal defects are difficult to reach using over-the-scope techniques. A novel, through-the-scope suture (TTSS) device allows direct closure of mucosal defects without scope withdrawal. We aim to evaluate the rate of delayed bleeding following the closure of large colon polyp EMR sites with TTSS.

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Published to PubMed This Week

• Clinically adjudicated reference standards for evaluation of infectious diseases diagnostics
  Clinical Infectious Diseases
• Intact fibroblast growth factor 23 concentrations in hypophosphatemic disorders
  Endocrine Practices
• Identification, measurement, and assessment of the clinical utility of human pancreatic polypeptide by liquid chromatography-tandem mass spectrometry
  Journal of Proteome Research
• Sebaceous carcinoma of the eyelid: proposed nomenclature for multifocal and multicentric disease
  Opththalmic Plastic Reconstructive Surgery
• Spectrum of renal pathological findings in patients with chronic myelomonocytic leukemia and kidney injury
  American Journal of Hematology
• Differential prognosis of single and multiple TP53 abnormalities in high count MBL and untreated CLL
  Blood Advisory
• Updates on LI-RADS treatment response criteria for hepatocellular carcinoma: focusing on MRI
  Journal of Magnetic of Resonance Imaging
• Isotopic composition of serum zinc and copper in healthy children and children with autism spectrum disorder in North America
  Frontiers in Molecular Neuroscience
• Hepatocellular carcinoma presentation and prognosis among Nigerian adults with and without HIV
  PloS One
  

Chantell Canfield

Chantell Canfield is a web content coordinator for Mayo Clinic Laboratories. She began working for Mayo Clinic in 2021.