Mayo Clinic Laboratory and Pathology Research Roundup: November 7, 2023
The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.
Cytomegalovirus (CMV) is a significant cause of morbidity and mortality among immunocompromised hosts, including transplant recipients. Antiviral prophylaxis or treatment is used to reduce the incidence of CMV disease in this patient population; however, there is concern about increasing antiviral resistance.
Published to PubMed This Week
- Population pharmacokinetic model of cefepime for critically ill adults: a comparative assessment of eGFR equations.
Antimicrobial Agents and Chemotherapy - Deep and repeated response to Trastuzumab Deruxtecan in a patient with human epidermal growth factor receptor 2-amplified large-cell Neuroendocrine Carcinoma with brain metastases: A case report.
JCO Precision Oncology - Mycobacterium abscessus subspecies identification using the Deeplex Myc-TB targeted NGS assay.
Journal of Clinical Microbiology - Liver disease progression in patients with alpha-1 antitrypsin deficiency and protease inhibitor ZZ genotype with or without lung disease.
Alimentary Pharmacology & Therapeutics - Extent of surgical resection as a predictor of tumor progression in skull base chordomas: A multi-center volumetric analysis.
World Neurosurgery - Lophomonas as a respiratory pathogen-jumping the gun.
Journal of Clinical Microbiology - Banff Digital Pathology Working Group: Image bank, artificial intelligence algorithm, and challenge trial developments.
Transplant International - Women 50 tears and older with negative pap test and positive human papillomavirus test for genotypes other than 16 and 18-follow-up outcomes.
Journal of Lower Genital Tract Disease - Fever, cough, and pancytopenia in a Transplant recipient.
Clinical Infectious Diseases - Identification of SARS-CoV-2 from human lung formalin-fixed paraffin-embedded tissue sections using mass spectrometry.
Omics - PAX8-positive (gynecologic-type) clear cell carcinoma metastatic to the Kkidney.
Mayo Clinic Proceedings - Incidence and outcomes of high bleeding risk patients with type 1 and type 2 myocardial infarction in a community-based cohort: Application of the academic research consortium high bleeding risk criteria.
International Journal of Cardiology
