Mayo Clinic Laboratory and Pathology Research Roundup: November 7, 2023

The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Use of next-generation sequencing to detect mutations associated with antiviral drug resistance in cytomegalovirus.

Cytomegalovirus (CMV) is a significant cause of morbidity and mortality among immunocompromised hosts, including transplant recipients. Antiviral prophylaxis or treatment is used to reduce the incidence of CMV disease in this patient population; however, there is concern about increasing antiviral resistance.

Read more.

Published to PubMed This Week

• Population pharmacokinetic model of cefepime for critically ill adults: a comparative assessment of eGFR equations.
  Antimicrobial Agents and Chemotherapy
• Deep and repeated response to Trastuzumab Deruxtecan in a patient with human epidermal growth factor receptor 2-amplified large-cell Neuroendocrine Carcinoma with brain metastases: A case report.
  JCO Precision Oncology
• Mycobacterium abscessus subspecies identification using the Deeplex Myc-TB targeted NGS assay.
  Journal of Clinical Microbiology
• Liver disease progression in patients with alpha-1 antitrypsin deficiency and protease inhibitor ZZ genotype with or without lung disease.
  Alimentary Pharmacology & Therapeutics
• Extent of surgical resection as a predictor of tumor progression in skull base chordomas: A multi-center volumetric analysis.
  World Neurosurgery
• Lophomonas as a respiratory pathogen-jumping the gun.
  Journal of Clinical Microbiology
• Banff Digital Pathology Working Group: Image bank, artificial intelligence algorithm, and challenge trial developments.
  Transplant International
• Women 50 tears and older with negative pap test and positive human papillomavirus test for genotypes other than 16 and 18-follow-up outcomes.
  Journal of Lower Genital Tract Disease
• Fever, cough, and pancytopenia in a Transplant recipient.
  Clinical Infectious Diseases
• Identification of SARS-CoV-2 from human lung formalin-fixed paraffin-embedded tissue sections using mass spectrometry.
  Omics
• PAX8-positive (gynecologic-type) clear cell carcinoma metastatic to the Kkidney.
  Mayo Clinic Proceedings
• Incidence and outcomes of high bleeding risk patients with type 1 and type 2 myocardial infarction in a community-based cohort: Application of the academic research consortium high bleeding risk criteria.
  International Journal of Cardiology

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.

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