Mayo Clinic Laboratory and Pathology Research Roundup: December 5

By Sarah Jarvis • December 5, 2023

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Fatal human rabies infection with suspected host-mediated failure of post-exposure prophylaxis following a recognized zoonotic exposure-Minnesota, 2021.

No human rabies post-exposure prophylaxis (PEP) failure has been documented in the United States using modern cell culture-based vaccines. In January 2021, an 84-year-old male died from rabies 6 months after being bitten by a rabid bat despite receiving timely rabies PEP. We investigated the cause of breakthrough infection.

Read more.

Published to PubMed This Week

• A case-control autopsy series of liver pathology associated with novel coronavirus disease (COVID-19).
  Annals of Diagnostic Pathology
• Molecular and clinicopathological features of granzyme B-negative extranodal NK/T-cell lymphoma.
  Human Pathology
• Malignant female genital tract smooth muscle tumors with adipocytic differentiation: A morphologic, immunohistochemical, MDM2 fluorescence in situ hybridization and molecular genetic study of 6 lipoleiomyosarcomas.
  Human Pathology
• Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: neurosurgical and otolaryngologic conditions.
  3D Printing in Medicine
• Impact of neoadjuvant chemotherapy on pathologic downstaging in patients with variant histology undergoing radical cystectomy.
  Clinical Genitourinary Cancer
• Assessment of sigma error metrics associated with manual secondary result review and subsequent artificial intelligence-driven quality assurance review-application to kidney stone analysis.
  Clinical Chemistry
• Anaplastic large cell lymphomas with equivocal DUSP22 FISH results: Recommendations for clinical reporting and diagnostic evaluation.
  Human Pathology
• Genetic features and outcomes of allogeneic transplant in patients with WT1-mutated myeloid neoplasms.
  Blood Advances
• Follicular lymphoma and diffuse large B-cell lymphoma with BCL2 and IRF4 rearrangements in adult patients.
  Human Pathology
• Outcomes of flap amputation after laser in situ keratomileusis.
  Cornea
• A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses.
  Frontiers in Immunology

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.