Mayo Clinic Laboratory and Pathology Research Roundup: January 23
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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.
Featured Abstract
Carcinoembryonic antigen-expressing oncolytic measles virus derivative in recurrent glioblastoma: a phase 1 trial.
Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a carcinoembryonic antigen-expressing oncolytic measles virus derivative (MV-CEA), was administered in recurrent GBM patients either at the resection cavity (Group A), or, intratumorally on day 1, followed by a second dose administered in the resection cavity after tumor resection on day 5 (Group B).
Published to PubMed This Week
- Venetoclax plus hypomethylating agents in DDX41-mutated acute myeloid leukaemia and myelodysplastic syndrome: Mayo Clinic series on 12 patients.
British Journal of Haemotology - The lymphoma epidemiology of outcomes cohort study: Design, baseline characteristics, and early outcomes.
American Journal of Hematology - HOCl-producing electrochemical bandage for treating pseudomonas aeruginosa-infected murine wounds.
Antimicrobial Agents and Chemotherapy - Temporal trends in antifungal susceptibility of cryptococcus neoformans isolates from a reference laboratory in the United States, 2011-2021.
Mycoses - Analysis of vitamin D3-sulfate and 25-hydroxyvitamin D3-sulfate in breastmilk by LC-MS/MS.
Journal of Chromatography - Cold platelet transfusion: The effects of a fluid warmer on platelet function.
Transfusion - Characteristics of normal weight Insulin-resistant adults with unfavorable health outcomes.
Metabolic Syndrome and Related Disorders - Detection of histoplasma capsulatum and blastomyces dermatitidis antigens in serum using a single quantitative enzyme immunoassay.
Journal of Clinical Microbiology - Lophomonas as a respiratory pathogen-jumping the gun.
Journal of Clinical Microbiology - Circulating immunophenotypes are potentially prognostic in follicular cell-derived thyroid cancer.
Frontiers of Immunology - Peripheral nervous system manifestations of MOG antibody associated disease.
Annals of Clinical and Translational Neurology - Extent of surgical resection as a predictor of tumor progression in skull base chordomas: A multicenter volumetric analysis.
World Neurosurgery
