When is it Cool to Drool? Oral Fluid Testing for Controlled Substance Monitoring

Feb. 5, 2025
11 a.m.–Noon CT

Cost

Free for all participants.

Overview

While routine and random urine drug testing has provided an objective measure of adherence to therapy in both the pain management and addiction settings, oral fluid has become an increasingly popular matrix to assess compliance. Since most urine drug collection is not observed, adulteration is possible, and other patients suffer from shy bladder or anuria and may not be able to provide a urine specimen. For these reasons, the utility of oral fluid has been explored as a tool to assess compliance. However, oral fluid is not without its analytical challenges such as low sample volumes and shorter windows of detection. 

This webinar will describe substance use disorders and the common laboratory tests and matrices used for controlled substance monitoring. The advantages and challenges of using oral fluid will be discussed along with how to correctly interpret oral fluid drug testing results.

Presenter

Paul Jannetto, Ph.D. 

Co-Director, Clinical & Forensic Toxicology Lab, Metals Lab, Clinical Mass Spectrometry Lab 
Consultant, Clinical Biochemistry
Associate Professor of Laboratory Medicine and Pathology
Mayo Clinic
Rochester, Minnesota

Learning objectives

Upon completion of this activity, participants should be able to:

  • Describe substance use orders and define oral fluid.
  • Identify the advantages and limitations of oral fluid for controlled substance monitoring.
  • Interpret oral fluid drug testing results.

Intended audience

This webinar is appropriate for any provider who monitors patients in addiction treatment or pain management settings, primary care internal medicine, family medicine, nurse practitioners, physician assistants, laboratory directors, lab supervisors, and laboratory send-out coordinators/managers.

Credit

The following types of credit are offered for this event:

ASCLS P.A.C.E.®

Mayo Clinic Laboratories is approved as a provider of continuing education programs in the Clinical Laboratory Sciences by the ASCLS P.A.C.E.® program. This program has been approved for a maximum of 1.0 P.A.C.E.® contact hour.

State of Florida

Mayo Clinic Laboratories is approved as a Continuing Education Accrediting Agency for the Clinical Laboratory Sciences for the State of Florida. Florida Board of Clinical Laboratory Personnel has designated this program for General (Clinical Chemistry/UA/Toxicology) credit. This program has been approved for 1.0 contact hour.

To obtain credit


1. Register for and participate in the program.

2. Complete the evaluation that will be sent to you after the program.

3. Generate and print your certificate(s).


Level of instruction for this program is basic.


Faculty disclosure


Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty members also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentations. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentations.

Questions

Contact us: mcleducation@mayo.edu

MCL Education

This post was developed by our Education and Technical Publications Team.