In an environment defined by constant change, successful organizations distinguish themselves not by predicting disruption, but by responding to it with clarity and purpose. William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, shared in Becker’s Hospital Review lessons on leading amid near-constant disruption. He emphasized the importance of building a disciplined approach to recognizing emerging trends and responding in ways that align with an organization’s strategy and strengths.

“Disruption alone does not create or capture value. Thoughtful, strategic response does,” says Dr. Morice.

This approach can help organizations turn disruption into an opportunity for growth and long-term success. Dr. Morice shared six practical takeaways for identifying and responding thoughtfully to a changing healthcare landscape.

• Monitor external trends broadly, but use your mission, strategy, and priorities to determine what truly matters.
• Explore new ideas with curiosity while using data, strategy, and operational realities to evaluate whether those ideas warrant action.
• Use a clear, adaptable strategy to prioritize resources, make decisions, and foster innovation aligned with organizational goals.
• Model multiple future scenarios to improve readiness and enable more confident, proactive decision-making amid uncertainty.
• Focus on experimentation and small-scale pilots over all-or-nothing moves to learn, adapt, and reduce risk before committing to major changes.
• Invest in people and capabilities through targeted professional development, strategic hiring, and collaboration to strengthen your organization while preserving institutional knowledge.

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