Mayo Clinic Laboratory and pathology research roundup: May 2

By Samantha Rossi • May 2, 2023

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Head-to-head comparison of MR elastography-based liver stiffness, fat Fraction, and T1 relaxation time in identifying at-risk NASH

The presence of at-risk nonalcoholic steatohepatitis (NASH) is associated with an increased risk of cirrhosis and complications. Therefore, noninvasive identification of at-risk NASH with an accurate biomarker is a critical need for pharmacologic therapy. We aim to explore the performance of several magnetic resonance (MR)-based imaging parameters in diagnosing at-risk NASH.

Read more.

Published to PubMed This Week

• Exercise capacity, NT-proBNP, and exercise hemodynamics in adults post-fontan.
  Journal of American College of Caridology
• Utility of flow cytometry screening before MRD testing in multiple myeloma.
  Blood Cancer Journal
• Clonally selected lines after CRISPR-Cas editing are not isogenic.
  CRISPR Journal
• Anaplastic kaposi sarcoma: A clinicopathologic and molecular genetic analysis.
  Modern Pathology
• Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.
  Cell Reports. Medicine
• Clinical validation of tagmentation-based genome sequencing for germline disorders.
  Journal of Molecular Diagnostics
• Novel initiatives are always welcome.
  European Heart Journal of Acute Cardiovascular Care
• Analytic result variation for high-sensitivity cardiac troponin: Interpretation and consequences.
  Canadian Journal of Cardiology
• Frequency of HER2 protein overexpression and HER2 gene amplification in endometrial clear cell carcinoma.
  Human Pathology
  

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.