Mayo Clinic Laboratory and Pathology Research Roundup: October 31

By Sarah Jarvis • October 31, 2023

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Hypoxaemia in patients with heart failure and preserved ejection fraction.

It is widely held that heart failure (HF) does not cause exertional hypoxaemia, based upon studies in HF with reduced ejection fraction, but this may not apply to patients with HF and preserved ejection fraction (HFpEF). Here, we characterize the prevalence, pathophysiology, and clinical implications of exertional arterial hypoxaemia in HFpEF.

Read more.

Published to PubMed This Week

• Rates among hospitalized patients with COVID-19 treated with convalescent plasma: A systematic review and meta-analysis.
  Mayo Clinic Proceedings
• Improving LC-MS/MS measurements of steroids with differential mobility spectrometry.
  Journal of Mass Spectometry and Advances in the Clinical Lab
• CDR2 and CDR2L line blot performance in PCA-1/anti-Yo paraneoplastic autoimmunity.
  Frontiers in Immunology
• Alterations in aquaporin-4-IgG aerostatus in 986 patients: A laboratory-based longitudinal analysis.
  Annals of Neurology
• Under the hood: The scientific leadership, clinical operations, statistical and data management, and laboratory centers of the antibacterial resistance leadership group.
  Clinical Infectious Diseases
• Priorities and progress in diagnostic research by the Antibacterial Resistance Leadership Group.
  Clinical Infectious Diseases
• Outcomes of transplant recipients with pretransplant Nocardia colonization or infection.
  Transplant Infectious Disease
• Sexual dysfunction in patients With metastatic breast cancer.
  Clinical Breast Cancer
• Membranous nephropathy-Diagnosis and identification of target antigens.
  Nephrology, Dialysis, Transplantation
• Updates in the classification of T-cell lymphomas and lymphoproliferative disorders.
  Current Hematologic Malignancy Reports
• Establishment of a labile bound copper reference interval in a healthy population via an inductively coupled plasma mass spectrometry dual filtration-based assay.
  Archives of Pathology & Laboratory Medicine
• Answer to the photo quiz: An unexpected visitor.
  Journal of Clinical Microbiology
• A pseudotumor in a mouse kidney following human MSCs injection.
  Stem Cell Reviews and Reports
• Diffuse hemispheric glioma with H3-3B G34R mutation: Expanding the spectrum of histone H3 genes in diffuse hemispheric glioma, H3 G34-mutant.
  Journal of Neuropathology and Experimental Neurology
• Effect of residual platelets in frozen-thawed plasma on results of dilute Russell's viper venom time assay for lupus anticoagulant testing.
  American Journal of Clinical Pathology
• Dependence of peripheral T-cell lymphoma on constitutively activated JAK3: Implication for JAK3 inhibition as a therapeutic approach.
  Hematological Oncology

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.