Mayo Clinic Laboratory and Pathology Research Roundup: April 9

By Sarah Jarvis • April 9, 2024

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial.

Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal cord injury (SCI). This Phase I trial (ClinicalTrials.gov: NCT03308565) included 10 patients with American Spinal Injury Association Impairment Scale (AIS) grade A or B at the time of injury. 

Read more.

Published to PubMed This Week

• Cytogenetic and pathologic characterization of MYC-rearranged B-cell lymphomas in pediatric and young adult patients.
  Journal of Hematopathology
• A review of histopathologic and radiologic features of non-atherosclerotic pathologies of the extracranial carotid arteries.
  The Neuroradiology Journal
• Fusion-driven cutaneous and superficial mesenchymal and adnexal tumors-A clinicopathologic and molecular study of 15 cases, including a novel case of ACTB::ZMIZ2-rearranged adnexal carcinoma.
  Journal of Cutaneous Pathology
• Elucidating the pathogenesis behind arteriovenous malformations of the central nervous system: a bibliometric analysis.
  Neurosurgical Review
• Performance of GPT-4 Vision on kidney pathology exam questions.
  American Journal of Clinical Pathology
• Using differential mobility spectrometry to improve the specificity of targeted measurements of 2,3-dinor 11β-Prostaglandin F2α.
  Clinical Biochemistry
• Autoimmune central nervous system disorders: Antibody testing and its clinical utility.
  Clinical Biochemistry
• Eosinophilic esophagitis: Does age matter?
  Journal of Pediatric Gastroenterology and Nutrition
• Case presentation of autoimmune septin-5 cerebellar ataxia.
  Movement Disorders Clinical Practice
• Serial bronchoalveolar lavage fluid aspergillus galactomannan and treatment response in invasive pulmonary aspergillosis.
  Open Forum Infectious Diseases
• Epidemiology, timing, and secondary prophylaxis of recurrent nocardiosis.
  Open Forum Infectious Diseases
• A call for universal definition of myocardial infarction after cardiac surgery.
  European Journal of Cardio-thoracic Surgery
• Automated mitotic spindle hotspot counts are highly associated with clinical outcomes in systemically untreated early-stage triple-negative breast cancer.
  NPJ Breast Cancer
• The impact of cytotoxic therapy on the risk of progression and death in clonal cytopenia(s) of undetermined significance.
  Blood Advances
• Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry.
  American Journal of Transplantation
• Commentary on severe hypokalaemia associated with paralysis after a large carbohydrate intake following exercise.
  Clinical Chemistry
• Emergence of TP53 mutation during lenalidomide therapy of myelodysplastic syndrome with del(5q) and its subsequent disappearance following salvage therapy with decitabine.
  Haematologica
• Secondary involvement of the urinary bladder by endometrial carcinoma.
  Mayo Clinic Proceedings
• Defective transfer of parental histone decreases frequency of homologous recombination by increasing free histone pools in budding yeast.
  Nucleic Acids Research

Sarah Jarvis

Sarah Jarvis is a Senior Marketing Specialist at Mayo Clinic Laboratories. She supports marketing strategies for paid media.