Mayo Clinic Laboratory and Pathology Research Roundup: March 30

By Samantha Rossi • March 30, 2020

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Echinococcus Multilocularis: First European Haplotype Identified in the United States: An Emerging Disease?

Echinococcus multilocularis is one of the most severe and lethal parasitic diseases of humans most often reported in Europe and Asia. Only one previous case has been documented in the contiguous United States from Minnesota in 1977. European haplotypes have been identified in carnivores and domestic dogs as well as recently in patients in Western and Central Canada. Via Clinical Infectious Disease.

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Published to PubMed This Week

• Risk of serious infection among individuals with and without low count monoclonal B-cell lymphocytosis (MBL).
  Leukemia
• Malignant Epithelioid Angiomyolipoma of the Kidney (Malignant Perivascular Epithelioid Cell Neoplasm).
  Mayo Clinic Proceedings
• Confirmation of 123 I-FP-CIT-SPECT (ioflupane) quantification methods in dementia with Lewy body and other neurodegenerative disorders.
  Journal of Nuclear Medicine
• Assessment of clinical outcomes with immune checkpoint inhibitor therapy in melanoma patients with CDKN2A and TP53 pathogenic mutations.
  PLoS One
• Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary.
  Circulation
• Cryptic and atypical KMT2A-USP2 and KMT2A-USP8 rearrangements identified by mate pair sequencing in infant and childhood leukemia.
  Genes and Chromosomes Cancer
• Comparison of the Panther Fusion respiratory panels to routine methods for detection of viruses in upper and lower respiratory tract specimens.
  Diagnoses of Microbiology and Infectious Disease
• Formalin pigment artifact deposition in autopsy tissue: predisposing factors, patterns of distribution and methods for removal.
  Forensic Science and Medical Pathology

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.