Mayo Clinic Laboratory and Pathology Research Roundup: September 7

By Samantha Rossi • September 7, 2020

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

99th Percentile Upper-Reference Limit of Cardiac Troponin and the Diagnosis of Acute Myocardial Infarction.

The 99th percentile of cTn remains the best-established criterion for the diagnosis of acute MI. While not perfect, it is analytically and clinically evidence-based. Until there are robust data to suggest some other approach, staying with the 99th percentile, a threshold that has served the field well for the past 20 years, appears prudent. Via Clinical Chemisty.

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Published to PubMed This Week

• Sensitivity-specificity of tau and Aβ PET in frontotemporal lobar degeneration.
  Annals of Neurology
• Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients.
  Mayo Clinic Proceedings
• Sex and Gender Disparities in the Management and Outcomes of Acute Myocardial Infarction-Cardiogenic Shock in Older Adults.
  Mayo Clinic Proceedings
• Amyloid Typing by Mass Spectrometry in Clinical Practice: a Comprehensive Review of 16,175 Samples.
  Mayo Clinic Proceedings
• Mucinous Carcinoma of the Breast.
  Mayo Clinic Proceedings
• Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens.
  Mayo Clinic Proceedings
• Prevalence of opioid induced adrenal insufficiency in patients taking chronic opioids.
  Journal of Clinical Endocrinology and Metabolism
• Primary Female Urethral Carcinoma: Proposed Staging Modifications Based on Assessment of Female Urethral Histology and Analysis of a Large Series of Female Urethral Carcinomas.
  American Journal of Clinical Pathology
• Assessing Utilization of the Cerebrospinal Fluid Venereal Disease Research Laboratory Test for Diagnosis of Neurosyphilis: a Cohort Study.
  Journal of Genetic Internal Medicine
• Upgrade at excisional biopsy after a core needle biopsy diagnosis of classic lobular carcinoma in situ.
  Surgery

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.