Mayo Clinic laboratory and pathology research roundup: November 16

By Samantha Rossi • November 16, 2020

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The research roundup provides an overview of the past week’s research from Mayo Clinic Laboratories consultants, including featured abstracts and a complete list of published studies and reviews.

Featured Abstract

Grading Chromophobe Renal Cell Carcinoma: Evidence for a Four-tiered Classification Incorporating Coagulative Tumor Necrosis.

Although grading systems have been proposed for chromophobe renal cell carcinoma (ChRCC), including a three-tiered system by Paner et al (Paner GP, Amin MB, Alvarado-Cabrero I, et al. A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear grade. Am J Surg Pathol 2010;34:1233-40), none have gained clinical acceptance, and the World Health Organization (WHO) currently recommends against grading ChRCC. Via European Urology

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Published to PubMed This Week

• Anti-Mullerian Hormone as a Serum Biomarker for Risk of Chemotherapy-Induced Amenorrhea.
  Journal of the National Cancer Institution
• Protein Contributions to Brain Atrophy Acceleration in Alzheimer's Disease and Primary Age-Related Tauopathy.
  Brain
• Education and Outreach in Physical Sciences in Oncology.
  Trends in Cancer
• Somatic Copy Number Gains in MYC, BCL2, and BCL6 Identifies a Subset of Aggressive Alternative-DH/TH DLBCL Patients.
  Blood Cancer Journal
• Recruitment Strategy for Potential COVID-19 Convalescent Plasma Donors.
  Mayo Clinic Proceedings
• Impact of the SARS-CoV-2 Pandemic on Emergency Department Presentations in an Integrated Health System.
  Mayo Clinic Proceedings
• Fibroadenoma of the Breast.
  Mayo Clinic Proceedings
• Anticoagulation in COVID-19: A Systematic Review, Meta-analysis, and Rapid Guidance From Mayo Clinic.
  Mayo Clinic Proceedings
• Striking Association of Lymphoid Enhancing Factor (LEF1) Overexpression and DUSP22 Rearrangements in Anaplastic Large Cell Lymphoma.
  American Journal of Surgical Pathology
• Bone Marrow Dendritic Cell Aggregates Associate with Systemic Immune Dysregulation in Chronic Myelomonocytic Leukemia.
  Blood Advances

Samantha Rossi

Samantha Rossi is a Digital Marketing Manager at Mayo Clinic Laboratories. She supports marketing strategies for product management and specialty testing. Samantha has worked at Mayo Clinic since 2019.